grd_kw = dict(left=0.2, right=0.8, bottom=0.3, top=0.9,
              wspace=0.3, hspace=0.2)
fig, ax = plt.subplots(2, 2, figsize=(8,6), gridspec_kw=grd_kw)
ax[0,0].plot(x, y)
ax[0,1].scatter(x, y)